There is a need in the office practice of otolaryngology for a safe and simple inhalation analgesic for minor surgical procedures. Such an analgesic is particularly adaptable to myringotomies and incisions of furuncles of the external canal, short but painful procedures.
Trichloroethylene (Trilene*) appears to be ideal for this purpose. The induction is rapid; no complicated apparatus is needed; no premedication is required; fasting is not necessary since nausea and vomiting do not occur, and recovery is rapid without side-effects. Virtually all of the trichloroethylene is removed from the body within a minute or so after the last inhalation.
Trichloroethylene is a stable, clear liquid, which is tinted blue by the manufacturer. Its odor is fruity and not unpleasant. Most important, it is nonexplosive and nonflammable when administered with air at room temperatures. The drug is relatively nonirritating to the
FELDMAN I. Inhalation Analgesia in the Office Practice of Otolaryngology. AMA Arch Otolaryngol. 1958;67(5):629–630. doi:10.1001/archotol.1958.00730010643025
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