Numerous studies have been reported regarding the clinical effectiveness of combinations of antibiotic drugs and cortisone derivatives in the local treatment of ear infections. The purpose of our study was to determine whether a combination of antibiotics with cortisone derivatives was more effective in the local treatment of ear infections than cortisone derivatives alone. We were also interested in determining, if possible, what particular clinical conditions were best suited to such local treatment.
Material and Method
This study is based on observations made in 268 patients from both private and clinic practice. All patients were ambulatory and were seen by one or the other of us. In every case a definitive diagnosis was made; treatment was prescribed, and follow-up observations were made. The study was limited to the following types of cases: (1) diffuse eczematoid external otitis; (2) external otitis secondary to surgery; (3) suppurative acute otitis media; (4)
RUBIN W, ANDERSON JR. Clinical Evaluation of Cortisporin Otic Solution. AMA Arch Otolaryngol. 1958;68(2):149–151. doi:10.1001/archotol.1958.00730020155003
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