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October 1958

Granular-Cell Myoblastoma of the Larynx

Author Affiliations

Washington, D. C.
From the Division of Otorhinolaryngology and Department of Pathology, Howard University College of Medicine and Freedmen's Hospital. Clinical Assistant Professor of Otorhinolaryngology, Division of Otorhinolaryngology (Dr. Hinton); Assistant Professor of Pathology, Department of Pathology (Dr. Weinberger).

AMA Arch Otolaryngol. 1958;68(4):497-500. doi:10.1001/archotol.1958.00730020517012

The following case report is that of a laryngeal tumor of the type first described in 1926 by Abrikossoff.1 This tumor, presumably composed of immature skeletal muscle elements, has been described variously as myoblastic myoma, granular-cell myoblastoma, myoblastoma, rhabdomyoma, and rhabdyome granulocellulaire. Although such tumors usually occur in sites where striated muscle is found, many have been reported from sites devoid of skeletal muscle. For this reason the exact origin of granular-cell myoblastoma remains obscure.2 We are concerned here with a granular-cell myoblastoma of the larynx.

In October, 1954, MacNaughtan and Fraser reported the 14th case of granularcell myoblastoma of the larynx and comprehensively reviewed the preexisting literature.3 In view of the paucity of reported cases of granular-cell myoblastoma of the larynx, we feel that the present case should be reported. This case was diagnosed and treated at Freedmen's Hospital, Washington, D. C., in 1956.