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February 1959

Histopathology of Olfactorius Due to Sarcomatosis of the Meninges: A Study with Silver Carbonate

Author Affiliations

Ann Arbor, Mich.
From the Laboratory of Neuropathology, Department of Psychiatry, University of Michigan Medical School.

AMA Arch Otolaryngol. 1959;69(2):143-150. doi:10.1001/archotol.1959.00730030149003

The olfactory bulb is exceptionally suited for studies of various pathological processes affecting the nervous system. This is due to the fact that in the bulb is located a complicated system of synapsis between the sensory cells and the second neuron. The complex functions require a support of the glial elements which are highly differentiated and are specific for the different layers.1 The present study is concerned with the cellular response to a slowly increasing pressure due to meningeal infiltration by a metastatic tumor. The importance of the findings is increased by the fact that the damage caused by pressure is slow and there is no infiltration of the tissues which would complicate the understanding of the pathological picture.

Material and Methods  The tissue for the present study was obtained on a postmortem examination of a 6-year-old girl with a sarcoma of the meninges of the spinal cord. This

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