Tumors causing a facial palsy may originate either from the facial nerve itself or from the acoustic nerve, with which the facial nerve is intimately connected intracranially. They may also arise from the surrounding tissues along the entire length of the facial nerve, producing a facial palsy either by compression of the nerve or by infiltration, according to the site and nature of the tumor.
The pathology of tumors of peripheral nerves has been described in a paper by Busch and Christensen on which the following general account is mainly based, partly by direct quotation.A peripheral nerve and its sheaths are formed in part from ectodermal tissue (axis cylinders, myelin sheaths, Schwann sheaths), and in part from mesodermal (epi-, peri-, and endoneurinum), and it is of fundamental importance to understand this structure in order to know which of its elements may form the point of origin for
KETTEL K. Peripheral Facial Palsies Due to Tumors: Pathology and Clinical Picture: A Review of the Literature and a Report of Three Cases of Intratemporal Tumors of the Facial Nerve. AMA Arch Otolaryngol. 1959;69(3):276–292. doi:10.1001/archotol.1959.00730030284004
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