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This monograph deals with cortisone and ACTH and their newer preparations such as hydrocortisone, Δ-cortisone, Δ-hydrocortisone, and fludrocortisone. Their chemical properties and physiological action; their influences on metabolism, inflammation, and the endocrine system, and their psychoneurologic relations are discussed.
When dealing with specific pathologic conditions of the ear, nose, and larynx, the authors find a wide range of usefulness of these preparations. In pathology of the external, middle, and internal ear, they discuss the various preparations and their mode of administration which are best applicable for each condition. Cortico-therapy has shown spectacular results in allergic conditions of the nose, polyposis, and acute sinusitis in both adults and infants. Associated with the antibiotics, cortisone has great value in acute suppurations of the pharynx, obstructive laryngitis, and acute corrosive lesions of the esophagus. Other conditions, such as adenitis, cervical spondylitis, and subacute parotitis, are favorably influenced by these preparations.
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