Otitis externa is a prevalent disease characterized by a multiple and overlapping etiology and a persistence in spite of intensive therapeutic measures. Inadequacies in current treatments are largely attributable to the lack of clear understanding of the underlying basis for external ear disease. In recent years, attempts have been made to examine and evaluate a variety of factors presumed to contribute to bacteriological, chemical, and pathological changes observed in external otitis.1,2 Evidence has been presented involving contamination; elevated temperature and humidity; maceration; removal of skin lipids; sweating; trauma; absence of cerumen; allergy; age, race, and sex; pH of surface secretions; anatomical configuration; stress, and individual susceptibility as predisposing elements, although their relative importance has not been determined.2 Obviously, a therapeutic approach directed at elimination or avoidance of etiologic factors is, at best, haphazard in view of the paucity of reliable information.
Successful therapy in otitis externa implies a
GOLDBERG SA. The Combination of Antimicrobials and a Corticoid (Florotic) for Treatment of Otitis Externa. AMA Arch Otolaryngol. 1959;70(1):139–142. doi:10.1001/archotol.1959.00730040143023
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: