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October 1959

Anaplastic Carcinoma of the Larynx Occurring in a Young Woman

Author Affiliations

Departments of Thoracic Surgery and Pathology, Huron Road Hospital, East Cleveland, Ohio.

AMA Arch Otolaryngol. 1959;70(4):466-470. doi:10.1001/archotol.1959.00730040476008

Carcinoma of the larynx is predominately a disease of males and is most frequently seen in the older age groups. Weinstein,1 in his case report, states that the average age of persons with disease is 60, and 92% of them are men. He reported a case of well differentiated squamous-cell carcinoma in a Negro woman, age 19, treated successfully by complete laryngectomy. In the series of 93 cases reported by Negus,2 90 were men, although his youngest patient was a woman, age 26. In the series reported by Martin,3 the youngest patient was a woman of 25. Other reports of laryngeal carcinoma are those of Lejeune and Lynch,4 age 20; Orton,5 age 12½; Walsh and Beamer,6 ages 12 and 13, and Jackson and Jackson,7 age 3 years. These cases, except that of Orton, showed no evidence of distant metastasis. In his case, metastases

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