Anaplastic Carcinoma of the Larynx Occurring in a Young Woman

Carcinoma of the larynx is predominately a disease of males and is most frequently seen in the older age groups. Weinstein,¹ in his case report, states that the average age of persons with disease is 60, and 92% of them are men. He reported a case of well differentiated squamous-cell carcinoma in a Negro woman, age 19, treated successfully by complete laryngectomy. In the series of 93 cases reported by Negus,² 90 were men, although his youngest patient was a woman, age 26. In the series reported by Martin,³ the youngest patient was a woman of 25. Other reports of laryngeal carcinoma are those of Lejeune and Lynch,⁴ age 20; Orton,⁵ age 12½; Walsh and Beamer,⁶ ages 12 and 13, and Jackson and Jackson,⁷ age 3 years. These cases, except that of Orton, showed no evidence of distant metastasis. In his case, metastases