In medical science, the bridge is often crossed precariously between experimental results in animals and the clinical application of these findings in humans. Rarely is the surgeon permitted an opportunity to observe the healing processes in the human following trauma to the stapes and oval window induced in mobilization procedures. We believed that a study of the tissue reactions in experimental animals following trauma similar to that induced in the course of human surgery would reveal interesting and valuable information. It is recognized, however, that results obtained in experimental animals cannot be interpreted as the same as those which accrue in human surgery. Nevertheless, information is acquired when animals are exposed to specific trauma, and this may influence the line of thinking regarding similar conditions in human surgery. In experimental animals, nature's method of healing and repair, and the responses of the delicate inner ear end-organs can be studied in
BELLUCCI RJ, WOLFF D. Experimental Trauma: Some Effects to the Otic Capsule and Their Possible Significance. AMA Arch Otolaryngol. 1960;71(2):224–231. doi:10.1001/archotol.1960.03770020096014
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