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September 1960

Granular-Cell Myoblastoma of the Larynx: Report of Three Cases

Author Affiliations

Associate Staff, Dept. of Otolaryngology, Detroit Receiving Hospital, and Assistant Professor of Otolaryngology, Wayne State University College of Medicine.

Arch Otolaryngol. 1960;72(3):314-320. doi:10.1001/archotol.1960.00740010322004

In 1926, Abrikossoff1 reported on several cases of a specific type of lesion which he called granular-cell myoblastoma. Since that time there has been considerable controversy about the nature and origin of this lesion; it has been the subject of many investigations and studies. Suffice it to say that this is a relatively uncommon lesion, only several hundred cases in the entire human body having been reported; of these only 16 have been found in the larynx and 7 in the tracheobronchial tree.6,16 It is then the purpose of this paper to describe three additional cases, two of which were encountered during the past few years at Detroit Receiving Hospital and one presented through the courtesy of Dr. Bruce Proctor.

As noted, the tumor is rarely found to involve the larynx. In a review of 1,197 benign lesions of the larynx, Holinger and Johnston10 mention only one

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