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November 1964

Osteogenic Sarcoma Of the Mandible: Report of Case Treated by Radiation and Chemotherapy

Author Affiliations

From the University of California, Los Angeles, School of Medicine, Department of Surgery/Head and Neck.

Arch Otolaryngol. 1964;80(5):566-570. doi:10.1001/archotol.1964.00750040580011

Osteogenic sarcoma occurring in the mandible is infrequent, judging from cases reported in the literature. The following case is reported because only a very few good therapeutic results have been achieved, all with radical surgical excision of the primary lesion.

In 1959 Richards and Coleman1 reviewed all reported cases of osteogenic sarcoma of the mandible. They found reports of 50 cases but excluded all but 17 because pathologic proof of the lesion was lacking. Although the ages of the patients ranged from 9 to 48 years, the majority were between 20 and 30. The outcome for six of the patients was not known, eight had recurrent or per

Fig 1.—Patient prior to therapy. sistent tumor and died, and three were alive and well after one year. A surgical excision of the lesion was performed in almost all patients, and supplementary radiation therapy was administered to five. The authors include

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