AS OVAL window surgery has become prominent in the field of otology, the untoward inner ear reactions of this surgery (eg, cochlear losses, persisting vertigo) have received much serious consideration.1-3,6,10,12,13 Various authors have suggested possible etiologic factors including intralabyrinthine injury from manipulation,6,11 drilling,12,13 compression of perilymph (pumping),2,6,10 bleeding into the vestibule or the technical difficulties resulting therefrom,2,3,12 infection,2,12 drill trauma,12,13 foreign protein in the vestibule,12,13 and severe otosclerotic disease.3 Harris and Weiss4 reported six granulomas of oval window fat grafts and concluded that they represented "minor variations upon a common theme of healing by cicatrization of injured, devascularized adipose tissue."
With the wide diversity of procedures, replacement materials, and the surgeon's individual skills, it is difficult to evaluate the differences in these techniques in terms of possible causes of inner ear reactions. This experiment was designed as a histopathologic study
HAYDEN RC, MCGEE TM. Traumatized Oval Window Fat Grafts. Arch Otolaryngol. 1965;81(3):243–249. doi:10.1001/archotol.1965.00750050252008
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