AUTOGENOUS fresh vein used to repair a defect in the tympanic membrane provides a bridge for the epithelium.1 Furthermore, the vein contributes its own substance, particularly elastic fibers, to the repair of the tympanic membrane. The present study was undertaken to ascertain the possible role that homologous lyophilized vein may play in the surgical repair of tympanic defects.
Materials and Methods
Defects in the tympanic membranes in two dogs were closed with portions of lyophilized jugular vein from another dog. In one dog (A116-61) a defect made four weeks earlier had healed, so a new perforation, 0.4 X 0.6 cm, was made in the inferior part of the tympanic membrane. The defect was repaired by placing a segment of lyophilized vein beneath the opening on the inner surface of the membrane. The vein segment was held in place by absorbable-gelatin-sponge (Gelfoam) packing in the middle ear and the external
GEORGE H. WILLIAMS, FRED R. GUILFORD, BELA HALPERT. Homologous Lyophilized VeinExperimental Study for Tympanic Closure in Dogs. Arch Otolaryngol. 1965;81(6):577–579. doi:10.1001/archotol.1965.00750050592009