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July 1965

Surgical Technique for Cryogenic Hypophysectomy

Author Affiliations


Arch Otolaryngol. 1965;82(1):32-37. doi:10.1001/archotol.1965.00760010034008

OUR PURPOSE is to present a technique of cryogenic hypophysectomy which has proven to be easier for the surgeon and safer for the patient than some other methods, while still achieving the desired result: ablation of pituitary function. The technique is transeptal-transphenoidal hypophysectomy using a cryogenic probe.

Techniques for Hypophysectomy  The most common approach to the pituitary gland has been by anterior craniotomy. Hirsch1 and Cushing2 were the first to approach the gland by the transeptal method. They attempted to remove pituitary tumors.In 1952 Olivecronia4 first described the treatment of metastatic breast cancer by hypophysectomy. He advocated a transcranial approach. The extensive series by Ray and his associates4-6 has provided much of the present knowledge concerning the relevant physiology of hypophyseal surgery.Recent improvements in surgical instruments and techniques, by both neurosurgeons and otorhinolaryngologists, have brought about a reassessment of hypophysectomy via extracranial approaches.Besides

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