ALTHOUGH chemotherapy and antibiotics have markedly altered the prognosis in serious bone infections, continued reliance upon these agents in unresponsive situations can be unrewarding as well as hazardous. Analysis of the case histories of the following six patients will emphasize the ineffectiveness of antibiotic therapy in certain instances and reaffirm the need for adherence to basic surgical principles in the management of severe osseous inflammatory diseases.
Infections of the facial bones and upper passages were well known to the ancients.1 Much has been written by 19th- and 20th-century surgeons regarding the surgical and nonsurgical management of these infections. The treatises by Furstenberg2 and Mosher and Judd3 regarding the pathology, mode of extension, and surgical treatment of frontal bone osteomyelitis remain as pertinent today as they were 30 years ago. The anatomical peculiarity of the maxilla has been well recognized. The necessity for adequate drainage set forth by
RAZIM EA, FRIEDBERG SA. Frontal, Maxillary, and Mandibular Bone Infections. Arch Otolaryngol. 1965;82(1):67–73. doi:10.1001/archotol.1965.00760010069016
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