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Dr. Gorlin, professor and chairman of oral pathology, University of Minnesota, and Dr. Pindborg, professor and chairman of oral pathology of the Royal Dental College, Copenhagen, have researched the world literature and summarized over 100 syndromes, each of which has an oral or facial component, and have assimilated them in this compendium.
At present there is not complete agreement concerning what constitutes a syndrome, though Hypocrates and Galen both used the term to denote a group of regularly concurrent signs or symptoms that could result from several causes. Neither is there a uniform method of nomenclature, since many syndromes are classified according to eponym (Albright's syndrome), others according to etiology (crush syndrome), pathogenesis (dumping syndrome), anatomic location (occulodentodigital dysplasia), main symptom (progressive hemifacial atrophy), or some other characteristic.
Each syndrome has been given a separate chapter which begins with a list of synonyms followed by an historical resume, then a
CLEMIS JD. Syndromes of the Head and Neck. Arch Otolaryngol. 1965;82(2):207. doi:10.1001/archotol.1965.00760010209030
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