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March 1966

Nasal Polyps

Author Affiliations

From the Clinic of Allergy and Applied Immunology, Temple University School of Medicine and Hospital, Philadelphia.

Arch Otolaryngol. 1966;83(3):266-269. doi:10.1001/archotol.1966.00760020268017

THERE is no unanimity of opinion regarding the basic understanding of the predisposing or underlying factors that contribute to the production of nasal polyps. All attempts to classify them according to their site or origin, their dominant etiology, or their histologic appearance have failed to clarify their mechanism of formation. Progress is further hampered by the absence of a satisfactory experimental animal that could serve as a model for more intensive investigation. This presentation will concern itself chiefly with two questions; first, What do we actually know about polyps? and second, What are the objectives of treatment and how can they best be implemented?

The site of origin has been a matter of controversy for some time. Most authors1,2 feel that the majority of polyps arise within the sinuses and present themselves intranasally in the vicinity of their corresponding ostia. Sanders,3 however, believes that allergic polyps first originate