IDENTICAL twins provide us with an ideal opportunity to investigate the effects of both heredity and environment in the causation and course of many disorders and diseases.
Bilateral noncontiguous structures of the body may in a way be considered identical twins, but although they are mirror images of each other and come from the same egg they are never exactly identical. (The mother knows which twin is which.)
In order to obtain a large number of twins I wrote to all otological departments in the prominent colleges and subsequently to persons in all of the otolaryngological societies here and abroad. I repeatedly put notices in medical journals and in the journals of the American Hearing Society and the New York League for the Hard of Hearing. These efforts obtained for me only two pairs of identical twins one or both of whom had otosclerosis. However, ultimately I was able to
FOWLER EP. Otosclerosis in Identical Twins: A Study of 40 Pairs. Arch Otolaryngol. 1966;83(4):324–328. doi:10.1001/archotol.1966.00760020326006
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