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April 1966

Responses of Laryngeal Tissue to Granular Teflon in Situ

Author Affiliations

From Michael Reese Hospital and the Department of Otolaryngology, University of Illinois College of Medicine, Chicago.

Arch Otolaryngol. 1966;83(4):355-359. doi:10.1001/archotol.1966.00760020357014

SINCE the advent of the use of Teflon glycerine mixture as a method of augmenting the size of the paralyzed, displaced, or deformed vocal cord, the question of the effect of its immediate and long-term residence in that location has been paramount. The immediate effects have been noted by several observers.1-3 All agree there was, as a rule, a minimum of reaction. That which did occur was always manageable. In perhaps one third of the cases patients suffered a moderate degree of local discomfort. In this group there was a fairly marked local edema. In two instances there was a temporary edema of such degree that tracheotomy was required. Subsidence of these reactions was rapid, and the reactions did not interfere with a successful end result. However, the important and lingering question remained. What was the long-term effect? Did time suggest a risk of a possible neoplastic response?


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