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To the Editor: Doctors Rius and Mendoza are to be congratulated on their persistence in theorizing on the etiology of otosclerosis. Examination of these four illustrations, however, would not convince this reader that they have been taken from otosclerotic cases. One must return to their 1961 article where the otosclerotic pathology is obvious. Figure 3 of that series is the same area as Fig 3 in this series. In both figures greater magnification would have been of value. One gains the impression from the earlier photograph that the "fat"-containing cells are really in the lamellar bone adjacent to the globuli. It would be physiologically plausible for bone cells to secrete a lipid. The mere presence of "fat" need not imply degeneration.
Personally I do not find that otosclerosis arises primarily in the globuli interossei. These unique structures have a paucity of vascular supply and viable nuclei even in a 5-month
WOLFF D. NEW HISTOLOGICAL OBSERVATIONS OF LABYRINTHINE CAPSULE IN RELATION TO THE ETIOLOGY OF OTOSCLEROSIS-Reply. Arch Otolaryngol. 1966;83(5):507. doi:https://doi.org/10.1001/archotol.1966.00760020509033
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