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July 1966

Pharyngeal Leiomyosarcoma With Fever of Unknown Origin

Author Affiliations

From the sections of plastic surgery and otolaryngology and rhinology, Mayo Clinic and Mayo Foundation (Drs. Lillie and Devine), and departments of otolaryngology and rhinology (Dr. Fuller) and pathology (Dr. Van Vliet), Mayo Graduate School of Medicine, Rochester, Minn.

Arch Otolaryngol. 1966;84(1):96-98. doi:10.1001/archotol.1966.00760030098010

TUMORS OF SMOOTH muscle origin are extremely rare in the regions of the pharynx and upper respiratory tract. No record of a leiomyosarcoma in the posterior region of the pharynx or in the hypopharynx could be found on review of the literature. The present case is thought to represent such a tumor. Because of the rarity of this lesion, as well as the unusual presenting symptom of fever of unknown origin and the clinical course of recurrent chills and fever, this case is presented.

Report of a Case  Case History.—The patient, a 39-year-old white office supervisor, was in good health until nine months prior to admission, when he noted the gradual onset of weakness and fatigue. Results of an annual physical examination at that time were considered unremarkable. The weakness and fatigue continued along with a gradual loss of approximately 10 lb (4.5 kg) in spite of a good

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