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August 1966

Implantation of Autogenous Bone and Cartilage Into Bullae of Dogs

Author Affiliations

From the departments of otolaryngology and pathology, Veterans Administration Hospital and Baylor University College of Medicine, Houston, Tex. Dr. Shortreed's present address is Sarnia, Ontario, Canada.

Arch Otolaryngol. 1966;84(2):144-147. doi:10.1001/archotol.1966.00760030146006

CORTICAL iORTICAL BONE and cartilage are being used in man to reconstruct the ossicular chain when one or more of its components are absent or not suitable for repositioning.1-5 In order to investigate the viability of bone and cartilage so implanted, autogenous osseous tissue and cartilage were placed into the bullae of dogs. The contents of the bullae were removed for microscopic study three months or longer following implantation.

Materials and Methods  Eight mongrel dogs each weighing about 7 kg were used. Two operations were performed on each animal, one on the left and one on the right side, with a one-month interval between the two procedures. In one half of the animals the initial operation was on the right side and in the other on the left. Under intravenous sodium pentobarbital (Nembutal) anesthesia, an incision was made over the costochondral junction of the left lower rib cage, and

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