HISTOPATHOLOGICAL changes following human stapes surgery have been reported by several investigators.1-7 Lindsay1 reported bilateral stapes mobilization with early re-ankylosis and osteogenesis in the area of the annular ligament. Baron and Lindsay2 reported a successful case of fat graft, and Schuknecht et al3 observed a fat connective tissue graft that was converted to connective tissue. Shea et al4 reported a vein graft with its elastic layer unchanged for 21 months postoperatively. The vein was covered on the vestibular surface by flat endothelium and on the middle ear surface by connective tissue and flat epithelium continuous with the mucoepithelium of the middle ear. There is evidence that vein graft repair takes place in three months according to Shea et al.4 House5 reported calcification in the vein graft, and Ezquerro6 observed the vein graft remains as vein for at least 2½ years. Harris
REDDY J, SATALOFF J, LIU J. Histopathological Changes Following Bilateral Stapedectomy. Arch Otolaryngol. 1966;84(2):165–169. doi:10.1001/archotol.1966.00760030167009
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