THE MAIN interest of the case report presented here is that it describes an operative procedure for dealing with neoplasms involving the cribriform plate. These neoplasms are especially important since olfactory neuroepitheliomas—which are but slightly radiosensitive—are being recognized more frequently.
Report of a Case
A 53-year-old man—an office worker—presented with swelling of the nasal bridge of about six weeks' duration. He had had right epistaxis three weeks previously. Fig 1 shows his external appearance. The upper part of the nasal septum was widened and appeared "granulomatous." The Wassermann reaction was negative; the erythrocyte sedimentation rate showed a 22-mm fall in the first hour; sinus x-ray films showed no obvious lesion; the blood count was normal; x-ray film showed the chest was clear. A biopsy of the septal lesion (Fig 2) was histologically interpreted by two pathologists as adamantinoma, by a third as squamous cell epithelioma, and by a fourth
HARPMAN JA. Malignant Neoplasm Around the Cribriform Plate. Arch Otolaryngol. 1966;84(2):189–192. doi:10.1001/archotol.1966.00760030191013
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.