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September 1966

Multiple Primary Mixed Tumors of the Salivary Gland: A Case Report

Author Affiliations

From the Department of Otorhinolaryngology (Drs. Gates and Ritter) and the Department of Pathology (Dr. Mesara), University of Michigan, Ann Arbor.

Arch Otolaryngol. 1966;84(3):329-331. doi:10.1001/archotol.1966.00760030331013

THE BENIGN mixed tumor is statistically the most common salivary gland neoplasm.1 It is typically unicentric in location and uninodular in character.1,2 The occurrence of lesions in more than one salivary gland suggests lymphomatous, inflammatory, or metabolic disorders as their etiology, inasmuch as multiple primary mixed tumors are extremely rare. It is the purpose of this paper to present a patient who had two simultaneously occurring mixed tumors, one in the parotid, the other in the contralateral submandibular gland. Since this type of occurrence has not been described in the eight previously reported cases of multiple primary mixed tumors, this case is presented.

Report of a Case  A 58-year-old woman presented at the University of Michigan Medical Center in September 1963 with a ten-year history of an asymptomatic, nonenlarging mass under the left mandible. Also, for 18 months she had noted a slowly enlarging, nontender mass below and

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