PARADOXICALLY, although many antibiotics originally effective against staphylococci have been developed, serious staphylococcal infections are becoming increasingly common. Two major factors appear to be involved. First is the more frequent use of hospitals for care of patients with major illnesses and childbirth. The concentration in hospitals of the most susceptible elements in the population results in their being exposed to all of the prevalent pathogens but particularly to the ubiquitous Staphylococcus. Besides becoming infected themselves these patients may become carriers and transmit their staphylococci to members of the family. Almost all infants acquire such infections while in the hospital, and soon all members of the family become carriers, especially the mother. Second is the great ability of the staphylococci to develop tolerance to antibiotic agents to which they originally were susceptible. This is more of a problem with the Staphylococcus than with any other organism. First penicillin-resistant organisms
SAUNDERS WH. Respiratory Infections and Antimicrobial Therapy. Arch Otolaryngol. 1966;84(3):359–361. doi:10.1001/archotol.1966.00760030361021
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