AN AUDITORY impairment is one of the more common dysfunctions observed in subjects with a history of posticteric encephalopathy due to an Rh mismatch.1-5 Perlstein6 found that 50% of the children with kernicterus he evaluated manifested a hearing loss or an auditory aphasia or both. Hardy,7 in a survey of 48 Rh children, noted that the audiological findings revealed a neural auditory impairment in 55% of the patients assessed; an additional 14% were classified as having neural hearing deficits, plus auditory imperception. Thus a sensorineural hearing impairment independent of aphasia has come to be recognized as one potential sequela of neonatal jaundice due to Rh incompatibility. However, the histological studies and audiological investigations designed to obtain evidence regarding the site of the lesion causing this hearing impairment have been contradictory.
The consistency of the pathological reports which have noted bilateral cellular destruction in the central auditory system,
MATKIN ND, CARHART R. Auditory Profiles Associated With Rh Incompatibility. Arch Otolaryngol. 1966;84(5):502–513. doi:10.1001/archotol.1966.00760030504008
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