THE EXPERIENCE of the past three decades has demonstrated that irradiation can be a highly effective method of treatment for superficial or early cordal carcinoma, and similar success has been achieved in the treatment of small or superficial lesions of the epiglottis. Such therapy appears to be at its best in the treatment of carcinoma in situ and other superficially invasive carcinomas, some of which have their origin in leukoplakia.
In the event of failure, following irradiation therapy for such lesions, laryngectomy has usually been required. Proving the presence of recurrent or residual disease has at times been a problem, particularly in cases where persisting edema and generalized mucosal thickening have been evident following the initial treatment. Furthermore, the gross extent of a recurrent lesion (which may, of course, represent residual or persisting disease rather than recurrence in the strict sense of the word) has been difficult to evaluate, and
NORRIS CM, PEALE AR. Partial Laryngectomy for Irradiation Failure. Arch Otolaryngol. 1966;84(5):558–562. doi:https://doi.org/10.1001/archotol.1966.00760030560018
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