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January 1967

Cytology: An Adjunct in the Diagnosis of Carcinoma of the Larynx

Author Affiliations

From the departments of pathology and otolaryngology, Marquette University School of Medicine, and Milwaukee County General Hospital, Milwaukee. Dr. Frable is now at the Medical College of Virginia, MCV Station, Richmond.

Arch Otolaryngol. 1967;85(1):50-52. doi:10.1001/archotol.1967.00760040052010

EXFOLIATIVE cytology is a well established method which has been applied to an ever increasing number of organ systems, and has proven effective in the early diagnosis of carcinoma, particularly in the in situ stage. Recent emphasis on cytology has been directed to early detection of carcinoma of the oral mucosa. Koss1 describes a single instance in which cytology is used to diagnose carcinoma in situ of the larynx in a patient with "mere redness" of the vocal cords.

To determine the effectiveness of cytology in the diagnosis of carcinoma of the larynx, smears were obtained from the larynx in a small series of patients undergoing direct laryngoscopy. All patients were symptomatic and had either a suspicious-looking laryngeal lesion or the larynx could not be visualized adequately by indirect laryngoscopy. We were principally interested in whether suitable material for cytologic study could be obtained from scrapings of the

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