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Article
January 1967

Tonsillectomy and Hemoglobin C-C Disease: A Case Report

Author Affiliations

KANSAS CITY, MO
From the Department of Otolaryngology, Kansas City General Hospital and Medical Center. Dr. Fuller is now at Reynolds Army Hospital, Fort Sill, Okla.

Arch Otolaryngol. 1967;85(1):99-101. doi:10.1001/archotol.1967.00760040101020
Abstract

CLINICAL SIGNIFICANCE of abnormal human hemoglobin levels gained impetus with the advent of electrophoresis techniques. Pauling, in 1949, distinguished sickle cell hemoglobin by electrophoresis,1 followed by Itano and Neel in 1950, who found another abnormal hemoglobin trait termed type "C."2 A case of homozygous type C hemoglobin was first reported by Spaet in 1953.3 Subsequently, numerous hemoglobinopathies of genetic origin occasionally associated with anemia have been discovered. Clinical significance of these traits and disease states remains unclear. Recently a fatality following tonsillectomy in a case of hemoglobin S-C disease due to hemolytic crisis was reported which emphasized the need for a better understanding of these conditions.4 The decision to perform a tonsillectomy in a patient with chronic anemia found to be due to hemoglobin C disease was recently made, and represents the reason for the following case report.

Report of a Case  The patient, a 16-year-old

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