CLINICAL SIGNIFICANCE of abnormal human hemoglobin levels gained impetus with the advent of electrophoresis techniques. Pauling, in 1949, distinguished sickle cell hemoglobin by electrophoresis,1 followed by Itano and Neel in 1950, who found another abnormal hemoglobin trait termed type "C."2 A case of homozygous type C hemoglobin was first reported by Spaet in 1953.3 Subsequently, numerous hemoglobinopathies of genetic origin occasionally associated with anemia have been discovered. Clinical significance of these traits and disease states remains unclear. Recently a fatality following tonsillectomy in a case of hemoglobin S-C disease due to hemolytic crisis was reported which emphasized the need for a better understanding of these conditions.4 The decision to perform a tonsillectomy in a patient with chronic anemia found to be due to hemoglobin C disease was recently made, and represents the reason for the following case report.
Report of a Case
The patient, a 16-year-old
FULLER AM, HUNT R, BARELLI PA. Tonsillectomy and Hemoglobin C-C Disease: A Case Report. Arch Otolaryngol. 1967;85(1):99–101. doi:10.1001/archotol.1967.00760040101020
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