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THE NATIONAL Center for Health Statistics in October 1966 published the Mortality Statistics From Diseases Associated With Smoking, from 1950 to 1964. Two groups of diseases are considered: those causally related to smoking, namely cancer of the lung, cancer of the larynx, cancer of the lip, and chronic bronchitis, and those associated with smoking but where the evidence is not yet sufficient to establish a causal relationship. The latter group comprises arteriosclerotic heart disease including coronary disease, cirrhosis of the liver, emphysema, ulcer of the stomach, cancer of the esophagus, cancer of the oral cavity other than the lip, cancer of the bladder and other urinary organs, and noncoronary cardiovascular disease. JAMA (199:24 [Jan 23] 1967) carries an interesting study of cigarette smoking in dogs. After more than 420 days of smoking through a tracheostomy tube there was marked cardiac enlargement compared to controls, and pulmonary fibrosis and emphysema in
SHAMBAUGH GE. Additional Data on Smoking. Arch Otolaryngol. 1967;85(6):589–590. doi:10.1001/archotol.1967.00760040591003
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