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September 1967

Preoperative and Postoperative Management of Hypophysectomy Patients

Arch Otolaryngol. 1967;86(3):282-286. doi:10.1001/archotol.1967.00760050284008

THE ANATOMIC relationships of the pituitary gland and the importance of the hypothalamic-pituitary portal system have been outlined in the preceding paper of this symposium. The following is a condensation of an extended paper on the subject of the physiology and preoperative and postoperative management of hypophysectomy. In the interest of brevity only so much of the physiology will be presented as is directly pertinent to the management of such cases and which may be unfamiliar to the nonendocrinologically oriented physician. Molecular biology will be largely avoided. For greater detail in this regard, the reader is referred to (a) the standard textbooks of endocrinology, (b) Ezrin's1 excellent review in the Ciba Clinical Symposia, and (c) the review "Hormones of the Anterior Pituitary Body" by Friesen and Astwood.2

Posterior Pituitary Function.—The posterior lobe of the pituitary gland is now known to be a storage organ for two chemically