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December 1967

The Antibody Deficiency Syndrome: Clinical Considerations

Author Affiliations

Danville, Pa
From the Department of Otolaryngology and Bronchoesophagology, Geisinger Medical Center, Danville, Pa.

Arch Otolaryngol. 1967;86(6):685-690. doi:10.1001/archotol.1967.00760050687017

WE AS OTOLARYNGOLOGISTS are concerned with patients, especially children, who have frequently recurring infections in the upper respiratory tract. Tonsillectomy and adenoidectomy is the answer for those who have recurrent tonsillitis and adenoiditis. But all too frequently these same children continue to have recurrent acute nasopharyngitis, sinusitis, and otitis media. The latter is frequently followed by middle ear effusion.

Administration of the appropriate antibiotic for ten days usually controls these acute infections but administration of an antibiotic does nothing to prevent the next infection.

I have made a consistent effort to correct poor dietary habits in these patients but this alone is not enough to prevent recurrent infections.

Administration of vaccines, both stock and autogenous, would seem to be a logical step if the child is immunologically competent. In my experience vaccines have too often failed to maintain a child in good health. My understanding of why vaccines fail was

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