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January 1968

Laryngeal Hyperkeratosis Due to Primary Monilial Infection

Author Affiliations

From the departments of pathology (Dr. Tedeschi) and otolaryngology (Dr. Cheren), Framingham Union Hospital, Boston University Medical Center, Boston.

Arch Otolaryngol. 1968;87(1):82-84. doi:10.1001/archotol.1968.00760060084016

GABRIEL AND JONES1 suggest that hyperkeratosis should be used as a clinical description for white thickening of the vocal cords or ventricular bands and histologically would be categorized into either a benign condition known as focal keratosis or pachyderma laryngis and leukoplakia, a premalignant lesion when cellular atypia is found.

A recent observation of benign laryngeal hyperkeratosis due to primary laryngeal monilial infection is the basis for this report.

Report of a Case  A 42-year-old white man was first seen in October 1966 with a history of recurrent hoarseness during the preceding four months. On further questioning he stated that his voice has had a different quality between these episodes of hoarseness. There was no history of dysphagia, hemoptysis, cough, or weight loss. There is no personal or family history of diabetes mellitus. The patient has smoked approximately 20 cigarettes daily for the last 30 years. Chest examination was