OTOLOGIC surgeons have used many materials for myringoplasty, including vein graft,1,2 temporalis fascia, canal skin, dura,3 exogenous collagen,4 and freeze-dried aortic valve.5,6 Although clinical experience with the last mentioned graft material has not been extensive, it has yielded rather impressive results. The use of this material is relatively new. Cornish6 has reported results of over 30 cases in which 90% of the grafting was successful. Sataloff5 has reported a similar series of cases with equally good results. The follow-up has been restricted, by necessity, to macroscopic observation of the healed drum. No report has yet been made on the use of heart valves as eardrum grafting material in experimental animals.
The object of this paper is to study the reaction of human aortic valves heterografted into perforated guinea pig eardrums. Information regarding the behavior of these heterografts and the histologic repair process may then
Kosoy J, Sataloff J, Laughlin L. Aortic Valves in Myringoplasty. Arch Otolaryngol. 1968;87(4):364–367. doi:10.1001/archotol.1968.00760060366004
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