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April 1968

Skin Grafting of Experimental Lye Strictures

Author Affiliations

Edmonton, Canada
From the Department of Surgery and SurgicalMedical Research Institute, University of Alberta, Edmonton, Canada. Dr. Harrison is now with the Department of Surgery, University of British Columbia, Vancouver, Canada, and Dr. Kubota is now with the Department of Surgery, University of Kyoto, Japan.

Arch Otolaryngol. 1968;87(4):405-410. doi:10.1001/archotol.1968.00760060407013

THE INCIDENCE of burns of the esophagus due to the accidental or deliberate ingestion of corrosive substances is declining, but it is still a serious and distressing problem. The modern management of acute chemical burns to the esophagus has reduced the incidence of stricture, but it still occurs, necessitating complicated surgical procedures for its correction.

We have produced lye burns of the esophagus in dogs and prevented the subsequent development of stricture by early skin grafting. Its use in an initial clinical case ended fatally because of technical errors.

Experimental Lye Burns  Methods.—Experimental stricture was produced in a series of dogs using 5% sodium hydroxide. An ordinary Foley catheter was modified by plugging the distal end (C), and attaching a second balloon 12 cm proximal to the Foley balloon (Fig 1). Holes were made in the body of the catheter, and under endotracheal general anesthesia the catheter was introduced

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