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April 1968

Primary Amyloidosis of the Larynx

Author Affiliations

Columbus. Ohio
From the Department of Otolaryngology, Ohio State University College of Medicine, Columbus, Ohio.

Arch Otolaryngol. 1968;87(4):413-415. doi:10.1001/archotol.1968.00760060415015

LOCALIZED amyloidosis of the larynx is a rare condition. The total number of cases of localized amyloidosis of the larynx, together with their contiguous organs, reported since 1875 is 179 including this case report.1,2 A study by New and Erich,3 in 1938, of 722 cases of benign tumors of the larynx found nine cases. Holinger and Johnston,4 in 1951, in an analysis of 1,197 cases of benign tumors of the larynx only found two cases of amyloid tumor. McAlpine et al1,5 in 1963, in an analysis of 732 benign laryngeal tumors found a total of seven cases.

Burrow in 1875 first described the condition when three amyloid tumors in the larynx were found in a male patient at autopsy. The youngest case of laryngeal amyloidosis was reported by Della Vedova in 1934 in an Italian boy age 11 years, and the oldest case by Becker in

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