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June 1968

Giant Cell Tumor of Ethmoid: Complication of Paget's Disease of Bone

Author Affiliations

From the Departments of Pathology and Otolaryngology, Framingham Union Hospital, Framingham, Mass, and Boston University Medical Center, Boston.

Arch Otolaryngol. 1968;87(6):615-617. doi:10.1001/archotol.1968.00760060617012

SARCOMA complicating Paget's disease is a well-known, relatively common entity. Its incidence has been given as between 5% and 14%.1 On the other hand, a giant cell tumor (osteoclastoma) arising within Paget's disease is extremely rare and not well documented. Its importance, however, should be recognized because sarcomas complicating Paget's disease have an extremely poor prognosis while giant cell tumors arising within Paget's are not as aggressive as giant cell tumors orginating again.2

Hutter3 in 1963 reported five cases of benign giant cell tumor complicating Paget's disease, and McKenna4 one year later reviewed the world literature to 12 cases. Schajowicz2 reported an additional case in 1966.

This paper constitutes what we feel to be the 14th reported case of giant cell tumor complicating Paget's disease and the first reported case in the ethmoid bone.

Report of a Case  A 68-year-old white man was first seen