THE unfortunate rubella epidemic of 1964–1965 left a legacy of deformed children born to women who were exposed to or contracted the disease during pregnancy. The teratogenic effects of rubella virus upon the fetus of the pregnant woman are a major concern of the various medical sciences responsible for the evaluation and treatment of the products of these pregnancies. The multidisciplinary medical approach to the study of these unfortunate pregnancies has added greatly to our knowledge of the clinical course and multiple manifestations of this disease which have become known in the newborn infant as the "rubella syndrome." This entity includes ocular, auditory, cardiac, osseus, neurological, and hematological derangements.
The risk of abnormality in the fetus is unclear; however, Ingall's1 statement, "the risk is simply unacceptable," is very appropriate when one considers the severe consequences of this maternal disease that are manifest in fetal wastage and malformation of
ALFORD BR. Rubella—A Challenge for Modern Medical Science. Arch Otolaryngol. 1968;88(1):1–2. doi:10.1001/archotol.1968.00770010003001
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