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July 1968


Author Affiliations

Huntington Medical Arts Center 23 Green St Huntington, New York

Arch Otolaryngol. 1968;88(1):116-117. doi:10.1001/archotol.1968.00770010118028

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To the Editor.—In the November 1967 Archives I reported having observed patients with carcinoma of the larynx who had been exposed to insecticides which caused severe throat irritation. Dr. Snyder of the Sloan-Kettering Institute for Cancer Research requested further information on these patients.

Report of Cases  The short case histories follow:Case 1.—A 24-year-old white landscaper complained of increasing hoarseness. This patient has never smoked, rarely ingests alcohol, and states that in the four years in his vocation he has developed a severe throat irritation when using pesticides, especially Isotox spray (commercial name). This patient developed an epidermoid carcinoma on the anterior one-third of the left vocal cord and I performed a hemilaryngectomy on Aug 15, 1966.Case 2.—A 69-year-old white woman, a horticulturist, has never smoked or ingested alcohol, has spent approximately ten years in the florist business, mainly inside greenhouses with exposure to pesticides, Malathron 50 and

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