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Article
March 1969

Metastasizing Nasopharyngeal Angiofibroma: A Case Report

Author Affiliations

Joensuu, Finland

From the Department of Pathology (Dr. Hormia) and the Department of Otorhinolaryngology (Dr. Koskinen), Central Hospital of Northern Karelia, Joensuu, Finland.

Arch Otolaryngol. 1969;89(3):523-526. doi:10.1001/archotol.1969.00770020525014
Abstract

ANGIOFIBROMA of the nasopharynx is a rare tumor that is encountered almost exclusively in males. It is difficult to establish the time at which it begins as it is not noticed until it emits symptoms through obstructing the upper respiratory pathways.1 It is usually established shortly before puberty or in early adolescence. Several cases display a strong tendency to recurrence and a locally destructive mode of growth. A general statement in the literature is that this tumor is never malignant. However, there are reports that it may undergo a malignant, sarcomatous change.2-4 We were able to find in the literature only one case in which metastases were demonstrated. This was the study by Massoud and Awwad5 in which the authors stated that they had encountered in one case "extensive metastatic deposits in the cervical lymph nodes together with the occurrence in the same patient of suspected metastases

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