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Article
March 1969

The Complex Treatment of Patients Affected With Papillomatosis of the Larynx and Trachea

Arch Otolaryngol. 1969;89(3):552-556. doi:10.1001/archotol.1969.00770020554022
Abstract

IT HAS been repeatedly pointed out in the literature that papillomatosis of the larynx and trachea often recurs and not infrequently degenerates into a malignant tumor (Semon, 1894; Schollmeyer, 1936; Ch. Jackson and C. Jackson, 1939; L. R. Zak, 1954; B. A. Lemberskii, 1955; D. E. Chernov, 1957; I. A. Voznesenskaya, 1958; G. M. Mnukhina, 1959; A. S. Samokhvalova and A. V. Nezhintseva, 1961; M. I. Svetlakov, 1964, and others).

Numerous observations showed that a complex method of therapy, including surgical intervention and medicinal radiation treatment, gives the best results in the presence of the described disease (A. A. Smutneva, 1957; I. A. Voznesenskaya, 1958; Z. M. Grekova, 1958; A. I. Lisovskaya, 1959; A. S. Samokhvalova and S. N. Olenev, 1961; N. F. Lebedev, 1961, and others).

Nevertheless, even after such treatment, regenerations of the papilloma of the larynx and trachea often occur. With the aim of systematically preventing them

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