IT HAS been repeatedly pointed out in the literature that papillomatosis of the larynx and trachea often recurs and not infrequently degenerates into a malignant tumor (Semon, 1894; Schollmeyer, 1936; Ch. Jackson and C. Jackson, 1939; L. R. Zak, 1954; B. A. Lemberskii, 1955; D. E. Chernov, 1957; I. A. Voznesenskaya, 1958; G. M. Mnukhina, 1959; A. S. Samokhvalova and A. V. Nezhintseva, 1961; M. I. Svetlakov, 1964, and others).
Numerous observations showed that a complex method of therapy, including surgical intervention and medicinal radiation treatment, gives the best results in the presence of the described disease (A. A. Smutneva, 1957; I. A. Voznesenskaya, 1958; Z. M. Grekova, 1958; A. I. Lisovskaya, 1959; A. S. Samokhvalova and S. N. Olenev, 1961; N. F. Lebedev, 1961, and others).
Nevertheless, even after such treatment, regenerations of the papilloma of the larynx and trachea often occur. With the aim of systematically preventing them
Shilovtseva AS. The Complex Treatment of Patients Affected With Papillomatosis of the Larynx and Trachea. Arch Otolaryngol. 1969;89(3):552–556. doi:10.1001/archotol.1969.00770020554022
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