SINCE the last progress report on this important subject, by Saunders1 in 1966, a number of new concepts about respiratory infections have emerged and several new effective antimicrobial agents have been developed and accepted for use in respiratory system infections. It will be the purpose here to present a critical appraisal of these developments and to examine some of the general trends in microbial problems.
New Information and Trends
Resistant Organisms.—A few years ago, and at the last writing of this progress report, considerable attention was given to Staphylococcus aureus infections which had become resistant to the usual antimicrobial agents. As new chemotherapeutic agents were developed, staphylococci became less of a problem. Now, however, three other microbial groups have achieved prominence because they are responsible for stubborn problems especially in institutional environments. One group is the gram negative organisms (Pseudomonas aeruginosa, Proteus species or coliform organisms)2,3 which
Alford BR. Respiratory Infections and Antimicrobial Therapy. Arch Otolaryngol. 1969;90(1):112–114. doi:10.1001/archotol.1969.00770030114023
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