MANY materials have been used successfully for the reconstruction of the middle ear. Ossicular remnants are the most widely used material for this purpose. These autografts are well tolerated and even retain some viability.1 When no remnants are available, other types of grafts have been incorporated with varying degrees of success. These include homografts,2 autogenous tragal cartilage,3 soft tissue,4 polyethylene, wire, and other materials.5 In certain situations there is still a need for a substance that is packaged, sterile, nonantigenic, and readily available.
Raymond-Jones6 reported on the use of deproteinized, lyophilized calf bone as a stapedectomy prosthesis in humans. His initial results were encouraging, but there have been no further reports and no animal studies have been done. The purpose of this study was to examine the response of the monkey middle ear to this material. Since autogenous bone has such proven value
Taggart JP. Incus Replacement Grafts in Monkeys. Arch Otolaryngol. 1969;90(4):445–448. doi:10.1001/archotol.1969.00770030447007
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.