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October 1969

Clinical Study of Alum Precipitated Extract in Ragweed Rhinitis: A Clinical Study

Author Affiliations

Erie, Pa
From the Department of Otolaryngology, Hamot Hospital, Erie, Pa.

Arch Otolaryngol. 1969;90(4):509-512. doi:10.1001/archotol.1969.00770030511020

AS OTOLARYNGOLOGISTS, we are continually called upon to diagnose and treat allergic diseases of the nose, throat, and ears. One of the most common and satisfactorily treated diseases is seasonal allergic rhinitis either occurring in the spring or the fall. Certainly of all the allergic rhinitises, those to grasses or to ragweed are by far the most common. Today approximately 15% of the total population are affected by some form of seasonal disease. It therefore behooves us to recognize and to know a satisfactory, safe, and economic form of treatment. The purpose of this paper is to present a summary of a method for treating the etiological factor, namely ragweed pollen, and the results of this therapy.

Studies, demonstrating that precipitation with alum slow absorption of antigen and resulting in an adjuvant effect, have encouraged the use of alum-precipitated extracts in a treatment of persons with allergic rhinitis. In 1959

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