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April 1970

Early Paget's Disease of the Labyrinthine Capsule: Case Report and Bone Study

Author Affiliations

Los Angeles
From the departments of pathology and surgery, Division of Head and Neck Surgery, Otology Section, University of California, Los Angeles.

Arch Otolaryngol. 1970;91(4):341-345. doi:10.1001/archotol.1970.00770040499007

THE MAJORITY of reported cases of Paget's disease of the temporal bone have shown relatively advanced involvement of the labyrinthine capsule, so that it has not been possible to demonstrate the progression of abnormal changes. In the present study of early involvement of this structure, certain changes representing an exaggeration of normal remodeling processes are described, which progress to the more familiar appearance of Paget's disease. In this early stage of involvement, certain similarities to changes in the temporal bones of patients with otosclerosis are noted.

Report of a Case  The patient was a 68-year-old white woman with severe generalized arteriosclerosis. Following surgery for an abdominal aortic aneurysm, with Dacron-graft replacement, a retroperitoneal abscess, septicemia, acute bacterial endocarditis of the mitral valve, mycotic emboli to the left middle cerebral and coronary arteries developed, and the patient died from acute myocardial infarction. The patient was known to have Paget's disease for

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