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June 1970

Toluidine Blue in Diagnosis of Cancer of the Larynx

Author Affiliations

From the Department of Otolaryngology, Boston University Medical School, and University Hospital (Drs. Vaughan and Strong), Department of Pathology and Head and Neck Clinic, Boston Veterans Administration Hospital (Drs. Vaughan, Strong, and Incze), Harvard Medical School and Tufts Medical School (Dr. Incze).

Arch Otolaryngol. 1970;91(6):515-519. doi:10.1001/archotol.1970.00770040745004

In the larynx it is frequently difficult to identify carcinoma in situ, early infiltrating carcinoma, and the exact margins of an established carcinoma.

It has been found that the use of toluidine blue as a supravital stain during direct laryngoscopy is a reliable adjunct to the early and precise diagnosis of carcinoma of the larynx.

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