Changes in the sodium ion (Na+) and potassium ion (K+) concentration of the endolymph and the perilymph of the scala tympani and the scala vestibuli of the cochlea of the living guinea pig were measured with cation-sensitive glass microelectrodes. Intense acoustic stimulation increased the Na+ concentration and decreased the K+ concentration in the endolymph. The endolymphatic Na+ concentration did not return to the control level after intense and prolonged acoustic stimulation. Similar stimulation slightly decreased the K+ concentration in the perilymph of the scala vestibuli, but the Na+ and K+ concentration in the perilymph of the scala tympani showed no appreciable change.
Nakashima T, Sullivan MJ, Snow JB, Suga F. Sodium and Potassium Changes in Inner Ear FluidsAnin Vivo Study With Glass Microelectrodes. Arch Otolaryngol. 1970;92(1):1–6. doi:10.1001/archotol.1970.04310010027001
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