A herniation of cochlear epithelial cells through the apical basilar membrane was recognized in five squirrel monkeys and in two cats in the presence of endolymphatic hydrops. A transmeatal labyrinthotomy was performed on six of these animals. These six developed marked hyperplastic changes in the vestibule and the lower turn of the cochlea. Except for marked distention of Reissner's membrane, the preservation of cellular elements in the cochlear duct was relatively good in most cases. We postulate that the herniations occurred from a marked pressure increase of the endolymphatic space.
Hoshino T, Paparella MM. Apical Basilar Membrane Herniations and Hydrops. Arch Otolaryngol. 1970;92(2):114–117. doi:10.1001/archotol.1970.04310020012004
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