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October 1970


Arch Otolaryngol. 1970;92(4):411. doi:10.1001/archotol.1970.04310040099022

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To the Editor.  —The value of the studies described by Dr. Boyd lies not only in the development of "expectorant" drugs but in any light they may shed on the physiology and pathology of mucous secretion. With all of the work that has been done on mucociliary function, we still remain more or less in the dark regarding the nature of normal respiratory mucus and what factors control its rate of production and physical composition.In evaluating his findings one wonders if the vapor pressure of inspired air was controlled or monitored and in what position the experimental animal was maintained. The latter question is pertinent in considering whether secretions were moved by ciliary action or by gravity.One would hope that Dr. Boyd would incorporate mucociliary studies (Quinlan M, Salman S, Swift DL, et al: Measurement of mucociliary activity in man. Amer Rev Resp Dis99:13-23, 1969) in

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